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In the aftermath of their journey to another planet, Director Phil Coulson and the rest of the team were driven more than ever to put an end to the HYDRA organization. Little did they know that they were up against the deadliest threat they've ever faced – an extremely powerful Inhuman, Hive, who was transported back from Maveth in the body of their worst enemy, Grant Ward. The team was able to thwart and kill Hive and take down HYDRA, but they are all still mourning the death of fellow agent and Inhuman, Lincoln Campbell.
In light of the Sokovia Accords, and with HYDRA obliterated, S.H.I.E.L.D. has been legitimized again and no longer needs to operate in the shadows. Since the world presumes that Coulson is dead, the organization needed a new Director to be the face of the organization. Coulson finds himself back in the role as an agent and teamed with Mack, and together they are tasked with tracking down and confirming the presence of Enhanced people, aka Inhumans. They have been trying to track down and capture Daisy, aka Quake, who has gone rogue in an attempt to atone for sins from the past. But with the world believing that Daisy is a dangerous outlaw who has taken down banks and bridges, the new Director has no qualms about taking her down for good. Agent May is tasked with training specialist strike teams, and Fitz and Simmons have taken a big step forward in their relationship. But with Simmons' new promotion as Special Advisor to the Director in Science and Technology, Fitz, as well as her former team members, finds it hard to confide in or trust her since she's now the Director's confidant.
Robbie Reyes will roar into the lives of Agent Coulson and the team as a junkyard mechanic who can turn on a dime into the terrifying Ghost Rider. Will Robbie be a friend or foe to S.H.I.E.L.D. – as well as the world, itself? Meanwhile, Fitz discovers that socially awkward genius and friend Dr. Radcliffe has started putting the finishing touches on a new, secret invention.
To be added.
- Main article: Agents of S.H.I.E.L.D./Credits
- Clark Gregg as Phil Coulson
- Ming-Na Wen as Melinda May
- Chloe Bennet as Daisy Johnson
- Iain De Caestecker as Leo Fitz
- Elizabeth Henstridge as Jemma Simmons
- Henry Simmons as Alphonso Mackenzie
- John Hannah as Holden Radcliffe
- Natalia Cordova-Buckley as Yo-Yo Rodriguez
- Mallory Jansen as Aida
- Gabriel Luna as Robbie Reyes/Ghost Rider
- Lorenzo James Henrie as Gabe Reyes
- Lilli Birdsell as Lucy Bauer
- Jason O'Mara as Jeffrey Mace
- Parminder Nagra as Ellen Nadeer
- José Zúñiga as Eli Morrow
- Adrian Pasdar as Brigader General Glenn Talbot
- Max Osinski as Agent Davis
- Patrick Cavanaugh as Agent Burrows
- Alexander Wraith as Agent Anderson
|The Ghost||4.01||September 20, 2016||Jed Whedon & Maurissa Tancharoen||Billy Gierhart|
|Ghost Rider is coming, and S.H.I.E.L.D. will never be the same.|
|Meet the New Boss||4.02||September 27, 2016||Drew Z. Greenberg||Vincent Misiano|
|Daisy goes to battle Ghost Rider at a terrible cost, and Coulson faces the new Director, and his bold agenda surprises them all.|
|Uprising||4.03||October 11, 2016||Craig Titley||Magnus Martens|
|As Coulson, Mack and Fitz attempt to track down and neutralize a rogue group looking to end Inhuman Registration worldwide, Simmons and Dr. Radcliffe only have hours to save May before she succumbs forever to her mysterious illness.|
|Let Me Stand Next to Your Fire||4.04||October 18, 2016||Matt Owens||Brad Turner|
|As Ghost Rider’s quest for vengeance brings him into an explosive confrontation with S.H.I.E.L.D., Coulson and Mack must rely on an unlikely ally in their time of desperate need; and Daisy reunites with a familiar face to stop the Watchdogs.|
|Lockup||4.05||October 25, 2016||Nora Zuckerman & Lilla Zuckerman||Kate Woods|
|As Robbie Reyes struggles to control the Ghost Rider; S.H.I.E.L.D. infiltrates a high-security prison to unravel the secrets that haunt them all.|
|The Good Samaritan||4.06||November 1, 2016||Jeffrey Bell||Billy Gierhart|
|Robbie's shocking story on how he became Ghost Rider is finally discovered as Coulson and his team's lives hang in the balance.|
|Deals With Our Devils||4.07||November 29, 2016||DJ Doyle||Jesse Bochco|
|With the loss of half the team, the remaining members search for answers as the clock counts down for Ghost Rider.|
|The Laws of Inferno Dynamics||4.08||December 6, 2016||Paul Zbyszewski||Kevin Tancharoen|
|S.H.I.E.L.D. and Ghost Rider find themselves unlikely allies when the lives of all of Los Angeles hang in the balance.|