- Amy Acker previously worked with Joss Whedon on Angel and Much Ado About Nothing.
- Amy Acker previously worked with Clark Gregg in Much Ado About Nothing, who personally asked her to take the role of Audrey Nathan.
- Amy Acker portrayed Caitlin Strucker in the 20th Century Fox Television production The Gifted.
- Amy Acker is one of the actresses to portray characters for both Marvel Studios and DC Entertainment. She voiced Helena Bertinelli/Huntress in Justice League Unlimited.