- The storyline in Thor: The Dark World when Jane Foster was taken to Asgard was added to the film so that Anthony Hopkins and Natalie Portman could share a scene together.
- Anthony Hopkins previously worked with Tessa Thompson in Westworld.
- Anthony Hopkins previously worked with Clive Russell in The Wolfman.
- Anthony Hopkins previously worked with Rene Russo in Freejack.
- Anthony Hopkins is one of the few actors in the Marvel Cinematic Universe to have won an Academy Award. He won the Academy Award for Best Actor at the 64th Academy Awards for his performance as Hannibal Lecter in The Silence of the Lambs.