The Collector's Museum was an intergalactic vault and holding area located at the Knowhere mining colony under the control of Taneleer Tivan, used to store the various objects and specimens in Tivan's collection.
Asgardians Sif and Volstagg arrived at the museum to deliver the Aether to the Collector. They were introduced to the infamous Tivan by Carina, and willingly gave the Aether to him, not realizing that he was apparently seeking the other Infinity Stones.
The Guardians of the Galaxy arrived to give the Orb to Tivan. Tivan explained to the Guardians that it was an Infinity Stone. Upon discovering this, Carina attempted to escape from slavery by grabbing the Stone, which disintegrated her and caused a huge explosion. The Guardians got out unscathed and Tivan suffered a minor head injury, but all of the creatures escaped.
- In the comics, the Collector's collection was so vast that he had museums on a number of different planets to house it. This was alluded to in a statement by James Gunn where he mentioned that the Collector might have other museums elsewhere.
- Many people believed the "Yellow Creature" in the museum is Beta Ray Bill, but James Gunn has confirmed that it is not.