At the beginning of World War II, Czechoslovakia was occupied by Nazi Germany. In 1942, the infamous Nazi general Reinhard Heydrich was assassinated by the Czech resistance. In retaliation, the Schutzstaffel troops burned the town of Lidice.
In November 1943, Steve Rogers witnessed a map showing the location of HYDRA facilities in Europe while liberating the prisoners in the Austrian HYDRA Weapons Facility. For that he was tasked to destroy all those facilities with a team while MI6 focused on locating the central HYDRA Headquarters.
By April 1945, the Nazi forces were suffering defeats on almost all battlefields of Europe. Around the time of Adolf Hitler's death, a delegation of German and Czech industrialists left the city of Prague to meet Allied representatives and hand over the occupied Czechoslovakian territories.