Scarlet Witch, in conjunction with a plan she made with Ultron and her brother Quicksilver, used her powers to manipulate the Avengers, with the exception of Hawkeye. Bruce Banner, affected by her powers, went into a state of uncontrollable rage and transformed into Hulk, traveling from the Salvage Yard to Johannesburg. Black Widow would normally have calmed Hulk down, but she had been affected by Scarlet Witch's powers herself, preventing her from helping.
Iron Man arrived on the scene and equipped the Hulkbuster armor, ordering the police to "stand down" and drawing the attention of Hulk. He attempted to calm Hulk down through conversation but inadvertently enraged him by referring to him as Bruce Banner. Hulk then threw a car at Iron Man but he managed to catch it. Hulk hit him through the car and sent him backwards, so Iron Man took off and grabbed Hulk by the neck, dragging him through the street. Hulk kicked the Hulkbuster armor, freeing himself and crashing Iron Man.
When Iron Man rose, Hulk ran at him but the Hulkbuster easily threw him off with the left arm before blasting him with the repulsor cannon on its right, making Hulk hit the side of a building first and then a delivery truck. Iron Man approached the truck but Hulk hit him from behind with a metal pole. He then pounced on the Hulkbuster before Iron Man could recover and severely damaged its left arm but as Hulk tore through the thick armor, Iron Man reversed the damaged arm and punched him off.
Hulk recovered almost instantly and charged at Iron Man. Seeing that the left arm of the suit was too damaged, Iron Man ejected it and called the hovering "Veronica" carrier for a replacement. He continuously barraged the charging Hulk with repulsor blasts from his right arm while the replacement attached itself to the Hulkbuster. Finally, Hulk punched Iron Man but he punched back with his new arm, causing a shockwave.
Iron Man managed to throw Hulk down on the ground and proceeded to pound him repeatedly with the new arm. Hulk grabbed hold of the arm but it turned out to be a trap, imprisoning Hulk's hand. Iron Man then attempted to fly Hulk away from the city, but Hulk punched him mid-air, causing him to crash into a building full of people. Iron Man tried to sedate Hulk but Hulk kicked him into an elevator full of people. He grabbed the elevator wire before it crashed, allowing the people to escape. Hulk jumped on him but the Hulkbuster flip-kicked him away before smashing him with the elevator and punching him full in the face, making him lose a tooth. Hulk angrily spit out the tooth, scaring Iron Man enough to apologize.
The fight spilled out once again, with Hulk angrily gliding the Hulkbuster across a tall building before ripping out vital components off of it. Veronica attempted to replace the damaged parts but Hulk smashed the incoming replacement right into the carrier, destroying both. Seeking to end the fight quickly, Iron Man flew high above the city, throwing Hulk into a building under construction, shooting missiles to destabilize it and ramming Hulk all the way to the ground floor, burying them both under the rubble.
Hulk burst through the rubble and began to calm down as the South African Army arrived on the scene. Hulk started to get angry again but Iron Man punched him in the head, knocking him unconscious.
- "The news is loving you guys. Nobody else is. There's been no official call for Banner's arrest, but it's in the air."
"Stark Relief Foundation?"
"Already on the scene. How's the team?"
"Everyone's... We took a hit. We'll shake it off."
"Well for now I'd stay in stealth mode, and stay away from here."
- ―Maria Hill and Tony Stark
Repairs began in Johannesburg following the incident and continued to as late as May 3, 2016 when Johannesburg was among the cities noted by WHiH Newsfront anchor Christine Everhart to be still "on the mend" as a result of the incidents involving the Avengers, in part due to their tactical response, as the issue of the Avengers' management and responsibility was being discussed.
- Avengers: Age of Ultron
- WHiH Newsfront
- Avengers: Infinity War (mentioned)