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As Ghost Rider’s quest for vengeance brings him into an explosive confrontation with S.H.I.E.L.D., Coulson and Mack must rely on an unlikely ally in their time of desperate need; and Daisy reunites with a familiar face to stop the Watchdogs.
To be added
- Clark Gregg as Phil Coulson
- Ming-Na Wen as Melinda May
- Chloe Bennet as Daisy Johnson/Quake
- Iain De Caestecker as Leo Fitz
- Elizabeth Henstridge as Jemma Simmons
- Henry Simmons as Alphonso Mackenzie
- John Hannah as Holden Radcliffe
- Gabriel Luna as Robbie Reyes/Ghost Rider
- Mallory Jansen as Aida
- Axle Whitehead as JT James/Hellfire
- José Zúñiga as Eli Morrow
- Lilli Birdsell as Lucy Bauer
- Kerr Smith as Joseph Bauer
- Phil Tyler as Watchdog #1
- Sergio Enrique as Guard
- Tanner Fontana as Elliot
- Unknown Actress as Agent Elizabeth Albee
- Unknown Actor as Sean
- Los Angeles, California
- Washington, D.C.
- Pasadena, California (mentioned)
- Pasadena Momentum Laboratory (mentioned)
- Canada (mentioned)
- Ontario (mentioned)
- Phil Coulson's Prosthetic Hand
- Hellfire Chain
- Rapid Bone-Healing Pills (mentioned)
- Darkhold (mentioned, photo)
- Lie Detector (mentioned)
- The Positronic Man
- Robbie Reyes's Mother
- Gabe Reyes
- Daniel Whitehall
- Red Skull
- Nick Fury
- Jeffrey Mace
- Isaac Asimov
- Robert Silverberg
- Edward Bulwer-Lytton
- Lone Ranger
- Turing Test
- The title of this episode is a lyric from the song "Fire" by The Jimi Hendrix Experience. This is referenced in the episode by the character Elliot wearing a T-shirt with Jimi Hendrix on it.
- After the end of the chase of Robbie Reyes and the Hell Charger, Coulson says "I get his car now right? Ain't that how this works?". This is a reference to the car race between Danny Zuko and Leo Balmudo of the 1978 musical Grease, where the prize to be won was the car of the loser. Both car races took place on the Los Angeles River.
- Episode writer Matt Owens confirmed that some of the lines in the episode are homages to the popular videogame Overwatch. In particular, some of Jemma Simmons's catchphrases reference the British hero Tracer, while Hellfire shared many lines and similar features with the Australian character Junkrat.