- Lou Ferrigno is best known for his portrayal of Hulk in the TV series The Incredible Hulk, that was followed by three TV movies.
- Lou Ferrigno also voiced Hulk in the TV animated series The Incredible Hulk, alongside Neal McDonough as Bruce Banner.
- Lou Ferrigno is the father of Lou Ferrigno Jr., who appeared in the Agents of S.H.I.E.L.D. episode The Things We Bury.
- Lou Ferrigno was uncredited for his role in Avengers: Age of Ultron.