Due to Wilson Fisk's criminal empire, with connections to the Hand and Russians, in Hell's Kitchen a lot of members of the Kitchen Irish decided to work for him in order to gain more power. But when Fisk was defeated by Daredevil, all the members of the Kitchen Irish returned to their old organization despite their leader Nesbitt still holding a grudge against him for the betrayal.
In 2001, Frank Castle enlisted in the Marine Corps under the command of Colonel Ray Schoonover. Castle would later take part in the Battle of Fallujah and other historic combat operations in both Iraq and Afghanistan. After his long time in service, Castle finally returned to his home with his family. The next day, Castle took his family to Central Park, where they ended up in the middle of a three way mob fight and everyone in his family was killed. Castle survived after getting shot in the head, but at the hospital, a Do Not Resuscitate order was placed for him. Although he flatlined, he came back to life a few seconds later without any medical aid.
Following his family's death, Castle began a crusade of one man in order to wipe out all the criminals of the city including the men who killed his family.
One night, seeking to reestablish the Kitchen Irish's control over New York City, the members of the mafia family met at a restaurant to discuss the history and future of the Irish presence in Hell's Kitchen. They discussed how Wilson Fisk had taken over the underworld of the city and how Daredevil put him away. As Nesbitt, the leader of the Kitchen Irish, began giving a speech in which he called for sober reflection, George attempted to make a joke about them all being drunk only to be shut up by Nesbitt's glaring eye. While Nesbitt addressed the group George went to grab another drink but was stopped by Cullen while Nesbitt subtly insulted George for siding with Wilson Fisk's criminal empire, rubbing his head roughly before telling the group that they would take back New York City's drug trade now that Fisk was in Ryker's Island.
Nesbitt told the group that since now the Russians were dead and the Japanese had fled, the drug rings were ready to be taken, with George and the others cheering him on as he spoke. Just as Nesbitt rallied the men behind him, Frank Castle fired a shot through the wall which hit Nesbitt in the forehead, killing him instantly. The Kitchen Irish crew launched up and began firing back as bullets littered the room. George took a bullet to the throat and fell back onto his chair as he bled out and died. The attack killed all but one of them. Grotto escaped.
- "Where's this asshole's hand?"
- ―Police Officer
Grotto escaped and went to Josie's Bar where he met with Matt Murdock, Foggy Nelson and Karen Page. The trio promised to help him; Grotto then passes out due to blood loss. While Murdock and Nelson went to the crime scene, Page took Grotto to Metro-General Hospital.