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Lucy Bauer visits her old house in the middle of the night, which scares the family currently living there.
Robbie Reyes travels to work and as he's working, Quake visits him with a made up story of her car engine lighting on fire, forcing Reyes to play along. When they're finally alone, they discuss the Ghost Rider, and Johnson mentions Gabe Reyes, which pushes Reyes to attack her. They briefly duel, and Reyes knocks her out. As Jemma Simmons and Leo Fitz are researching a bizzare, invisible, material, Alphonso Mackenzie brings them details on Lucy Bauer and the house incident. The three question the existence of ghosts. Fitz and Mack get a lead and go to find her, without Simmons.
Phil Coulson and Melinda May talk to Jeffrey Mace, the new Director of S.H.I.E.L.D., after a 2-hour wait. They discuss Quake, and Mace says she needs to he dealt with before they legitamize S.H.I.E.L.D. again. Mace and Coulson lead a tour group, and May hallucinates multiple tour-members going demonic. Suddenly desperate for answers, May interrupts Chen in his cell and begs for a way to cure it. Chen only bangs his head on the glass until Jemma Simmons comes and puts him to sleep.
Lucy Bauer enters the Momentum Alternative Energy Laboratory and frees Hugo and Frederick from boxes similar to the one that held her. They discuss a book that can help them, and that they'll kill "him". They continue to free people like them.
Quake wakes up to discover Robbie Reyes tied her up. They begin to discuss the Aryan Brotherhood and Johnson mentions Momentum Labs. Reyes realizes this is a lead and leaves, although Johnson uses her powers to escape and follows.
Leo Fitz and Alphonso Mackenzie infiltrate Momentum Labs but are attacked by Frederick until Robbie Reyes intervenes. He transforms into Ghost Rider and murders Frederick, as Quake arrives. Ghost Rider grabs a picture and walks out. Melinda May's infection is beginning to make her insane. May begins to lash out against the STRIKE team until Jeffrey Mace reveals his Inhuman powers and knocks her out.
- Clark Gregg as Phil Coulson
- Ming-Na Wen as Melinda May
- Chloe Bennet as Daisy Johnson/Quake
- Iain De Caestecker as Leo Fitz
- Elizabeth Henstridge as Jemma Simmons
- Henry Simmons as Alphonso Mackenzie
- John Hannah as Holden Radcliffe (credit only)
- Jason O'Mara as Director Jeffrey Mace
- Gabriel Luna as Robbie Reyes/Ghost Rider
- Briana Venskus as Agent Piper
- Daniel Zacapa as Canelo
- Lilli Birdsell as Lucy Bauer
- Jen Kuo Sung as Chen
- Nico David as Boy
- John Churchill as Father
- Adrian Quinonez as Ignacio
- Dan Donohue as Frederick
- Ward Roberts as Hugo
- Usman Ally as Vincent
- Deren Tadlock as Cecilio
- Mark Daneri as Wisconsin Congressman
- Jenson Cheng as Chen's Thug #1
- Ken DuBois as Chen's Thug #2
- Victor Chi as Chen's Thug #3
- Edwin H. Bravo as Chen's Thug #4
- Unknown actress as Mrs. Serrano
- Los Angeles, California
- Pasadena, California
- New York City, New York (mentioned,computer screen)
- Houston, Texas (computer screen)
- Washington, D.C. (mentioned)
To be added
- Phil Coulson's Prosthetic Hand
- S.H.I.E.L.D. Lanyard
- Darkhold (mentioned)
- Rapid Bone-Healing Pills (mentioned)
- Momentum Labs
- United States Congress
- Strategic Scientific Reserve (mentioned)
- Watchdogs (mentioned)
- Sokovia Accords
- Joseph Bauer
- Eli Morrow
- Tobias Ford
- Gabe Reyes
- Peggy Carter
- Yo-Yo Rodriguez
- Lincoln Campbell (photo)
- Gordon (indirectly)
- President Matthew Ellis
- Steve Rogers
- Schrödinger's cat
- Nikola Tesla
- Paris Agreement
- The title of this episode is a lyric from the song "Won't Get Fooled Again" by The Who.
- When Daisy secretly reveals she knows information on Reyes, she mentions his uncle. In the comics, Reyes gets his powers from the demonic spirit of his uncle, Eli, who was a serial killer and Satanist when he was alive.