- Michelle Pfeiffer is one of the actresses to portray characters for both Marvel Studios and DC Entertainment. She portrayed Selina Kyle/Catwoman in Batman Returns.
- Michelle Pfeiffer portrayed Lamia in the comic book adaptation Stardust.
- Evangeline Lilly named Michelle Pfeiffer as her ideal choice for the role of Janet van Dyne in 2015.
- Michelle Pfeiffer previously worked with Paul Rudd in I Could Never Be Your Woman.