Midtown High School of Science and Technology was established in 1962.
Academic Decathlon Coach
|Wilson||Health & Physical Education||Teacher|
|Ronda Kramer||Art (formerly)||Teacher|
- Peter Parker
- Michelle Jones
- Liz Toomes (formerly)
- Flash Thompson
- Ned Leeds
- Betty Brant
- Abe Brown
- Charles Murphy
- Cindy Moon
- Sally Avril
- Tiny McKeever
- Seymour O'Reilly
- Jason Ionello
- In the comics, Peter Parker and Jessica Jones were classmates in Midtown High. Jones also had a crush on Peter.
- Midtown School of Science & Technology was established in 1962, as a reference to Spider-Man's first appearance in the comics in Amazing Fantasy Vol 1 #15.
- Howard Stark and Abraham Erskine appear in a mural in the school and Bruce Banner is among the famous scientists pictured in one of the classrooms.
- The school day ends at 2:45 pm.