Natalia Cordova-Buckley portrayed Elena "Yo-Yo" Rodriguez in the Agents of S.H.I.E.L.D. episode Bouncing Back, The Team, Emancipation, Absolution and Ascension in Season Three and The Ghost, Uprising, The Laws of Inferno Dynamics, Broken Promises, Wake Up, Self Control, Farewell, Cruel World!, The Return and World's End in Season Four.
She reprised the role in the web series Agents of S.H.I.E.L.D.: Slingshot.
She portrayed herself in Agents of S.H.I.E.L.D.: Academy.