- She was nominated for a Teen Choice Award for Choice Actress: Sci-Fi/Fantasy for her work on Thor: The Dark World.
- Natalie Portman was considered for the role of Black Widow in Iron Man 2.
- Natalie Portman is one of the actresses to portray characters for both Marvel Studios and DC Entertainment. She portrayed Evey Hammond in V For Vendetta.
- Natalie Portman is one of the actresses to portray characters for both Marvel Studios and Lucasfilm, both of which are owned by Walt Disney Pictures. She portrayed Padmé Amidala in Star Wars: Episode I – The Phantom Menace, Star Wars: Episode II – Attack of the Clones and Star Wars: Episode III – Revenge of the Sith.
- The storyline when Jane Foster was taken to Asgard was added to the film so that Natalie Portman and Anthony Hopkins could share a scene together.
- Natalie Portman previously worked with Stellan Skarsgård in Goya's Ghosts.