Project Mr. Blue is S.H.I.E.L.D.'s name for their research on Samuel Sterns' mind after being mutated by the blood of Bruce Banner.[1]
History
Agent Natasha Romanoff discovered an insane Samuel Sterns in the rubble of his apartment after his encounter with Emil Blonsky. She shot him in the leg and captured him after he tried to convince her to work for him.
Sterns was being held at a secure location and being studied by S.H.I.E.L.D. scientists.[2]
Gallery
Samuel Sterns mutating
Natasha shooting Dr. Sterns in the leg