Rome is the capital of Italy.
World War II
In 1943, Johann Schmidt and his HYDRA division went rogue, separating themselves from the Nazi regime and intended to nuke the capitals of all countries that would resist his conquest, including Rome.
Hunt of Bruce Banner
Italian Living Standard
Ian Quinn spent some time in Rome, visiting a hairdresser who charged him thirty dollars for a haircut. Quinn compared its cost to the five dollars Ernesto charged him for the same haircut and shave at the barbershop in Cuba that served as John Garrett's headquarters.