- Rosario Dawson auditioned for the role of Gamora in Guardians of the Galaxy.
- She starred alongside Michael B. Jordan and Kurtwood Smith in the 2017 video game Wilson's Heart.
- Rosario Dawson is one of the actresses to portray characters for both Marvel Studios and DC Entertainment. She voiced Wonder Woman in Justice League: Throne of Atlantis and Justice League Dark and Barbara Gordon/Batgirl in The Lego Batman Movie.
- Rosario Dawson also portrayed Gail in the comic book adaptations Sin City and Sin City: A Dame to Kill For.
- Rosario Dawson also portrayed Laura Vasquez in the comic book adaptation Men in Black II.