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- "Tower, this is S.H.I.E.L.D. Echo-3. I got a pair of UAVs on my six. These friendlies? Over."
- ―John Garrett
During the HYDRA Uprising, Victoria Hand sent two S.H.I.E.L.D. UAVs to assassinate John Garrett by shooting down his Jump Jet because she believed Garrett was an agent of HYDRA. As the drones were firing upon him, he radioed the Bus carrying Coulson's Team for assistance. Manned by Phil Coulson, the Bus was able to destroy both UAVs as Garrett and Coulson coordinated their attack. Meanwhile, in the Hub, Hand, with four other agents she knew was loyal to S.H.I.E.L.D., watched on radar as Garrett's plane docked with the Bus; she planned to deal with him when the Bus arrived there.