- "My family heirloom is a magic staff-slash-wand."
- ―Nico Minoru
PRIDE's First Ritual
The Staff of One was found by Nico Minoru while exploring her mother's office. She briefly reminisced about her older sister Amy, accidentally making it snow. She had Alex Wilder come over to the Minoru household to stop the snow, hiding the fact from Tina in the process.
Kidnapping of Alex Wilder
To be added 
- "An electrical current just traveled from your neural pathways into the staff and made that happen."
"You can explain it anyway you want, but it needed my blood and read my mind. It’s just like Wicca."
"It is science, Nico."
"If by science you mean high-tech magic, then sure."
- ―Tina Minoru and Nico Minoru
- "What, are you gonna blast me with that thing? Go ahead."
"I was thinking of smacking you with it."
- ―Leslie Dean and Tina Minoru
In order to revive Victor Stein, PRIDE decided to sacrifice one of their members. While Janet Stein was to be sacrificed, her lover Robert Minoru decided to sacrifice himself out of guilt for not being there to save Amy, much to Tina's concern. While Jonah deemed Robert as "dispensable," Tina used the Staff of One to disintegrate the capsule that was to sacrifice Robert. Leslie Dean was angered by Tina's actions, as one of the only people who knew how to make the capsule was "legally dead." At this, Tina threatened to use the Staff in melee combat against Leslie, but was halted by Jonah.
Battle at the PRIDE Construction Site
- "Stuck around for more lessons, I would've shown you how to do that."
- ―Tina Minoru to Nico Minoru
Nico brought the Staff of One with her to aid her friends in stopping PRIDE. She attempted to use it to fill up a hole dug up by PRIDE, but Tina cancelled the command by summoning the Staff back to her hand. Tina later used the Staff to block attacks from Chase Stein's Fistigons and Karolina Dean's beams of light, but she was soon disarmed by Jonah.
Because the Staff of One is designed to respond to Tina Minoru's DNA, Tina is one of the only ones who can use it, as can Nico by the virtue of being her daughter. Anyone else who tried to wield it while it was active would be burned by it, forcing them to drop it and making it deactivate. When it is active, it can read what the user desires and can bring it forth, though it seems to have some limitations, such as when it failed to disable a vehicle, despite Nico asking it to do so.
- Weapon Summoning - Tina was able to call the Staff from Nico's grasp to her hands. Presumably, Nico could do the same with more knowledge of the device.
|Appearances for the Staff of One|
In chronological order:
- In the comics, the Staff of One is a powerful staff powered by blood magic capable of summoning any spell and incantation that exists, but can only do each spell once. The Staff of One was used by the powerful dark wizard Tina Minoru, but was later stolen by her daughter Nico Minoru.
Behind the Scenes
- Unlike in the comics, where the Staff of One resides inside Nico Minoru's body and is summoned whenever she shed her own blood, the staff exists as a device that needs only a drop of blood to be used. These changes were made to avoid any controversy for inciting self-harming behavior.
- The Staff of One is powered by some advanced technology. Runaways showrunner Josh Schwartz commented: "It may not be from this world."