|Strategic Scientific Reserve|
|Notable members|| Chester Phillips|
|Locations|| United States of America|
|Movie||Captain America: The First Avenger|
|TV series||Agents of S.H.I.E.L.D.|
|Comic|| Captain America: First Vengeance|
Captain America: The First Avenger Adaptation
The Avengers: The Avengers Initiative
|Status||Absorbed into S.H.I.E.L.D.|
- "The Strategic Scientific Reserve is an Allied effort made up of the best minds in the free world. Our goal is to create the best army in history. But every army starts with one man."
- ―Chester Phillips
The Strategic Scientific Reserve was formed in 1940 on the orders of President Franklin D. Roosevelt. Though the United States wasn't directly involved in World War II at the time, Roosevelt knew that such situation was only temporary, because Adolf Hitler and his Third Reich were the greatest threat to the free world.
The commanding officer of the S.S.R. was Colonel Chester Phillips. The same year when the S.S.R. was formed, he persuaded the American industrialist Howard Stark to join the agency, after the group of assassins sent by HYDRA, Hitler's special weapons division, tried to kill them both. Shortly after, they organized the rescue of Abraham Erskine from Castle Kaufmann where he was being held by Johann Schmidt, the commanding officer of HYDRA. Phillips sent one of his best agents, Peggy Carter, to secure Erskine's release.
The S.S.R. was formed of greatest minds of the Allied nations who assembled to battle the Nazis in occupied Europe. The goal of the S.S.R. was to create an army of super soldiers that could defeat anything the Axis powers had on the battlefield. This led to the Project Rebirth based on the work of their newest acquisition, Erskine, and transformation of Steve Rogers into Captain America.
In November 1943, several members of the S.S.R. were in Italy. When Steve Rogers discovered that his friend Bucky Barnes was captured by HYDRA, he flew behind enemy lines and led a successful escape of prisoners from the HYDRA factory in Austria. 
In 1945, the efforts of the S.S.R. were successful. HYDRA was destroyed, and the Axis powers defeated. The S.S.R. continued for a short time after the war, taking on cases such as the Zodiac, but was disbanded in 1946 and its former membership absorbed into a new agency, S.H.I.E.L.D..
After the formation of S.H.I.E.L.D., the S.S.R. became the scientific division of the agency, making weapons and inventions for the organization and training gifted young adults to become S.H.I.E.L.D. scientists.