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Union City was a mining town who benefited of suppliance of natural gas, but the contamination of the aquifers led the majority of the citizens to leave the town.
In 2016, the Inhuman known as Hive purchased Union City with the purpose of using it both as a base for both him and his Inhuman thralls and a place for Holden Radcliffe to work at trying to recreate the experiment used by the Kree to conceive the Inhumans.
Soon after, Union City became the battleground of a brutal three-way struggle between Hive and his Inhumans, S.H.I.E.L.D., and a pair of Kree Reapers summoned to Earth by Hive to help complete Radcliffe's experiment. The fight ended with the Reapers dying, and after Radcliffe's experiments proved unsuccessful, the Inhumans were forced to abandon Union City.