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Uprising may refer to:
- Agents of S.H.I.E.L.D.: Uprising - An event that served as a tie-in of the Agents of S.H.I.E.L.D. television series with the Captain America: The Winter Soldier movie.
- Uprising (episode) - A third episode of the fourth season of the television series Agents of S.H.I.E.L.D. and the sixty-ninth episode overall.