Having Inhuman lineage, Monica remained at a place called the "Afterlife" and was among those that were selected to undergo the process of Terrigenesis. After emerging from her cocoon, Monica's powers were activated and soon left the Afterlife with a number of Inhumans that refused to follow Jiaying's attempt to wage war on the Humans and S.H.I.E.L.D..
At some point during the Inhuman Outbreak, Monica was recruited into S.H.I.E.L.D. by Jeffrey Mace, who became the organization's new director. Earning a promotion as chief of the Artificial Intelligence division, Monica also became a member of the reformed Secret Warriors.